Halting coronavirus polymerase

Research output: Contribution to journalArticle

Abstract

© 2020 Kirchdoerfer. The nucleotide analogue remdesivir is an investigational drug for the treatment of human coronavirus infection. Remdesivir is a phosphoramidate prodrug and is known to target viral RNAdependent RNA polymerases. In this issue, Gordon et al. identify that remdesivir acts as a delayed RNA chain terminator for MERS-CoV polymerase complexes.
Original languageEnglish
JournalJournal of Biological Chemistry
Volume295
Issue number15
DOIs
StatePublished - 10 Apr 2020

Fingerprint Dive into the research topics of 'Halting coronavirus polymerase'. Together they form a unique fingerprint.

  • Cite this