Supplementary Material for: Inpatient Care during the COVID-19 Pandemic: A Survey of Italian Physicians

  • Marina Attanasi (Contributor)
  • Simone Pasini (Contributor)
  • Antonio Caronni (Contributor)
  • Giulia Michela Pellegrino (Contributor)
  • Paola Faverio (Contributor)
  • S. DiPillo (Contributor)
  • Matteo Maria Cimino (Contributor)
  • Giuseppe Cipolla (Contributor)
  • Francesco Chiarelli (Contributor)
  • Stefano Centanni (Contributor)
  • G.F. SferrazzaPapa (Contributor)
  • for the RECOVER Investigators Study Group Collaborators (Contributor)



<b><i>Background:</i></b> Coronavirus disease 2019 (COVID-19) is a potentially fatal disease that is of great global public health concern. <b><i>Objective:</i></b> We explored the clinical management of inpatients with COVID-19 in Italy. <b><i>Methods:</i></b> A self-administered survey was sent by email to Italian physicians caring for adult patients with COVID-19. A panel of experts was selected according to their clinical curricula and their responses were analyzed. <b><i>Results:</i></b> A total of 1,215 physicians completed the survey questionnaire (17.4% response rate). Of these, 188 (15.5%) were COVID-19 experts. Chest computed tomography was the most used method to detect and monitor COVID-19 pneumonia. Most of the experts managed acute respiratory failure with CPAP (56.4%), high flow nasal cannula (18.6%), and non-invasive mechanical ventilation (8%), while an intensivist referral for early intubation was requested in 17% of the cases. Hydroxychloroquine was prescribed as an antiviral in 90% of cases, both as monotherapy (11.7%), and combined with protease inhibitors (43.6%) or azithromycin (36.2%). The experts unanimously prescribed low-molecular-weight heparin to patients with severe COVID-19 pneumonia, and half of them (51.6%) used a dose higher than standard. The respiratory burden in patients who survived the acute phase was estimated as relevant in 28.2% of the cases, modest in 39.4%, and negligible in 9%. <b><i>Conclusions:</i></b> In our survey some major topics, such as the role of non-invasive respiratory support and drug treatments, show disagreement between experts, likely reflecting the absence of high-quality evidence studies. Considering the significant respiratory sequelae reported following COVID-19, proper respiratory and physical therapy programs should be promptly made available.
Date made available5 Aug 2020
PublisherFigshare - Karger

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